Scientists identify mutated protein linked to Alzheimer’s disease risk

Study finds Alzheimer's disease risk connected to newly discovered protein

Washington [US], September 21 (ANI): According to a new USC study, a mutation in a newly discovered small protein is connected to a significant increase in the risk for Alzheimer’s disease, expanding the known gene targets for the disease and presenting a new potential avenue for treatment. The protein, called SHMOOSE, is a tiny “microprotein” […]

Mutation in newly discovered small protein linked to increase in Alzheimer's disease risk

A mutation in a newly discovered small protein is connected to a significant increase in the risk for Alzheimer's disease, expanding the known gene targets for the disease and presenting a new potential avenue for treatment, according to a new USC study.

Researchers Discover Mutated Protein Linked to Increased Risk of Alzheimer’s Disease

A new mutated protein has been discovered that is connected to a significant increase in the risk of an individual contracting Alzheimer’s disease, according to a study by the University of Southern California (USC).

Mitochondrial DNA variation in Alzheimer’s disease reveals a unique microprotein called SHMOOSE - Molecular Psychiatry

Mitochondrial DNA variants have previously associated with disease, but the underlying mechanisms have been largely elusive. Here, we report that mitochondrial SNP rs2853499 associated with Alzheimer’s disease (AD), neuroimaging, and transcriptomics. We mapped rs2853499 to a novel mitochondrial small open reading frame called SHMOOSE with microprotein encoding potential. Indeed, we detected two unique SHMOOSE-derived peptide fragments in mitocho…

Newly discovered protein connected to Alzheimer’s disease risk

A mutation in a newly discovered small protein is connected to a significant increase in the risk for Alzheimer’s disease, expanding the known gene targets for the disease and presenting a new potential avenue for treatment, according to a new USC study.

Scientists identify mutated protein linked to Alzheimer’s disease risk

Story at a glance  Alzheimer’s disease affects 5 million people in the U.S., according to data from 2020. Researchers are working to understand the various risk factors that may contribute to devel…