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What’s so Special About Orange Cats? Turns Out They’re Freaks of Nature | News Channel 3-12

  • Scientists identified a specific DNA deletion mutation causing the orange fur color in domestic cats in a study published May 15 in Current Biology.
  • Researchers found this unusual mutation only in domestic cats and not in wild cats or other animals, suggesting it arose once during domestication and was selectively bred for.
  • The mutation involves a 5,076-base-pair deletion on the X chromosome that activates the gene Arhgap36, which blocks black pigment and shifts pigment production to orange pheomelanin.
  • Lead author Christopher Kaelin called it "a really unusual type of mutation" and noted the findings could provide new insights into genetic mechanisms and feline evolution.
  • The discovery offers tools to trace domestic cat evolution and raises questions about similar mutational mechanisms in other genes and species.
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What’s so special about orange cats? Turns out they’re freaks of nature

Researchers identified an unusual genetic mutation in orange domestic cats that has not been found in any other animal, according to a new study.

·Atlanta, United States
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petsradar.com broke the news in on Tuesday, May 20, 2025.
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