Early Detection of Emerging SARS-CoV-2 Variants From Wastewater Through Genome Sequencing and Machine Learning
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3 Articles
3 Articles
Early detection of emerging SARS-CoV-2 Variants from wastewater through genome sequencing and machine learning
Genome sequencing from wastewater enables accurate and cost-effective identification of SARS-CoV-2 variants. However, existing computational pipelines have limitations in detecting emerging variants not yet characterized in humans. Here, we present an unsupervised learning approach that clusters co-varying and time-evolving mutation patterns to identify SARS-CoV-2 variants. To build our model, we sequence 3659 wastewater samples collected over t…
·United Kingdom
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