US EditionA Century-Old Lung in a Jar Yields Clues to the Spanish Flu’s Lethal Surge
ZURICH, SWITZERLAND, AUG 7 – Researchers sequenced the earliest complete influenza A genome from July 1918, revealing key mutations that helped the virus adapt to humans before the pandemic's deadliest wave.
Summary by ZME Science
4 Articles
4 Articles
Through the medical archives, some silent tissues retain the traces of forgotten events. Conserved since 1918 in a jar of formol, the lungs of a Swiss teenager carried away by a mysterious pneumonia have just delivered a secret of a global reach. Thanks to the progress of paleogenomics, researchers have been able to reconstruct the genome of the Spanish flu from this century-old sample, revealing the early mutations that allowed the virus to ada…
Spanish flu virus genome reconstructed from 107-year-old lung • Virus had key adaptations to humans earlier than previously thought • Detailed understanding of virus adaptation refines models for future pandemic threats
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