Real-time component-based particle size measurement and dissolution prediction during continuous powder feeding using machine vision and artificial intelligence-based object detection - Pharma Excipients

Real-time component-based particle size measurement and dissolution prediction during continuous powder feeding using machine vision and artificial intelligence-based object detection - Pharma Excipients

This work presents a system, in which machine vision combined with artificial intelligence-based image analysis was used to determine the component-based particle size distribution of pharmaceutical powder blends. The blends consisted of acetylsalicylic acid (ASA) and calcium hydrogen phosphate (CHP). Images of powders were recorded with a digital camera in-line during feeding from a continuous feeder. The component-based particle size distribut…