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Re: Stepwise dual antiplatelet therapy de-escalation in patients after drug coated balloon angioplasty (REC-CAGEFREE II): multicentre, randomised, open label, assessor blind, non-inferiority trial

Summary by The BMJ
Agreement: I AgreeBody: Dear Editor Gao et al. 2025 investigate the efficacy and safety of a stepwise de-escalation strategy for dual antiplatelet therapy (DAPT) following drug-coated balloon (DCB) angioplasty. This study addresses a pertinent clinical query regarding the optimization of antiplatelet therapy pot-DCB angioplasty [1]. Finding the equilibrium of thrombotic risk reduction and minimizing bleeding remains a key principle of Evidence-b…

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The BMJ broke the news in on Wednesday, April 2, 2025.
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