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Pfizer COVID-19 vaccine sales tumble after government guidance on the shots narrows

Pfizer's profit guidance rises despite a 25% drop in Comirnaty vaccine sales due to narrowed federal recommendations and delayed updated shot approvals, officials said.

  • This season, Pfizer's Comirnaty sales started slowly after federal regulators narrowed eligibility, with U.S. revenue falling to $870 million in the third quarter as delayed approval also hurt sales.
  • Following changes at the CDC last month, federal guidance adopted recommendations from advisers picked by U.S. Health Secretary Robert F. Kennedy Jr., shifting booster advice and confusing drugstore customers.
  • At Bay Street Pharmacy in Sebastian, Florida, Theresa Tolle said this fall has been confusing, with some customers declining shots and others fearful, while some locations required prescriptions.
  • Public health experts warn vaccine rates have been suboptimal in recent years and could fall further this season, while Wall Street analysts expect Moderna's Spikevax sales to tumble about 50%.
  • A major industry group and insurers clarified coverage as America's Health Insurance Plans said members will cover shots and CVS Health announced earlier this month it will not require prescriptions after sales rose first two quarters of the year and Moderna prepares third-quarter results Thursday.
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WKYC broke the news in Cleveland, United States on Tuesday, November 4, 2025.
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