US EditionParkinson’s Breakthrough Could Unlock Treatments for Devastating Disease
Researchers used ASA-PD imaging to visualize over 1.2 million alpha-synuclein oligomers, revealing larger clusters in Parkinson’s brains linked to disease progression.
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8 Articles
Scientists observe Parkinson's 'trigger' in human brain tissue
New Delhi, Oct 02: Scientists have, for the first time, directly visualised the way Parkinson’s disease gets ‘triggered’ in human brain tissue. Using a newly developed technique, called ASA-PD (Advanced Sensing of Aggregates for Parkinson’s Disease), researchers from the University of Cambridge and University College London, UK, could see, count, and compare the protein clusters called alpha-synuclein oligomers in human brain tissue. Oligomers h…
Technology can play an important role in supporting the development of diagnostics and potential treatments, according to the study, which also included the participation of researchers from the University of Montreal, Canada.
Scientists have visualized and quantified for the first time in human brain tissue the groups of proteins considered as triggers of parkinson, a breakthrough that can mark a milestone in the study and the fight against neurological disease that grows more rapidly in the world. Researchers from the University of Cambridge have achieved it, [...] The entry Scientists visualize for the first time the trigger of parkinson in the brain was first publ…
The Elusive Trigger Behind Parkinson's Disease Finally Unveiled
For the first time, researchers have successfully visualized and quantified small protein clusters in the human brain that may signal the onset of Parkinson’s disease. These clusters, known as alpha-synuclein oligomers, have long been implicated in some of the fastest-expanding neurological disorders worldwide but had never been observed in brain tissue until now. To identify [...] The post The Elusive Trigger Behind Parkinson’s Disease Finally …
The finding is an advance in the knowledge of the early development of this pathology. The details of the research, led by the University of Cambridge (United Kingdom), are published in Nature Biomedical Engineering magazine. “For a long time these clusters were suspected to be present, and this study helps to confirm it. This is an important step, since being able to see them allows researchers to understand how they contribute to the disease,”…
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