Optimized solvent conditions improve drug retention and targeting in lymph node metastasis

Optimized solvent conditions improve drug retention and targeting in lymph node metastasis

Optimizing drug delivery to the lymphatic system is essential for effective cancer treatment, as lymph node (LN) metastasis is a critical factor influencing patient prognosis. A research team led by Professor Tetsuya Kodama from the Graduate School of Biomedical Engineering at Tohoku University has published new findings that clarify how the physicochemical properties of therapeutic formulations govern lymphatic and vascular flow dynamics.