US EditionOpportunities in IgA Nephropathy Research: Exploring the 4 Hit Process
- IgA nephropathy is a progressive autoimmune kidney disease primarily affecting adults aged 20 to 40 worldwide.
- The disease develops through the 4 hit process, involving immune complexes with Gd-IgA1 accumulating in the kidneys.
- Symptoms vary and may initially be subtle or absent, including hematuria, proteinuria, fatigue, and high blood pressure.
- Dr. Edgar Lerma emphasized the importance of accurately recognizing and diagnosing IgA nephropathy, noting that it is commonly identified in individuals between their twenties and forties.
- Otsuka pursues advanced research and treatments targeting APRIL and the 4 hit process to improve patient outcomes and care.
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Opportunities in IgA Nephropathy Research: Exploring the 4 Hit Process
(StatePoint) IgA nephropathy is a progressive, autoimmune, chronic disease that predominantly affects adults between the ages of 20 and 40, with an annual global incidence of 2.5 cases per 100,000 people. Despite its prevalence, IgA nephropathy remains a challenging disease…
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Leaning Left6Leaning Right6Center27Last UpdatedBias Distribution69% Center
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C 69%
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