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One dose of psilocybin changes the human brain, leading to higher entropy

The findings suggest stronger entropy during the trip predicted greater insight, and 70% of participants reported improved well-being two to four weeks later.

Summary by Medical Xpress
Researchers at UC San Francisco and Imperial College London have shown that a single dose of psilocybin, the psychedelic compound found in magic mushrooms, causes likely anatomical brain changes that last for up to a month after the experience.

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Scientific American broke the news on Tuesday, May 5, 2026.
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