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Novartis Continues RNA & Neuroscience Growth Strategy With $12B Avidity Bio Acquisition

Novartis will pay $12 billion in cash to acquire Avidity Biosciences and enhance its neuroscience pipeline with innovative RNA therapeutics for genetic neuromuscular diseases.

  • On Sunday, Switzerland-based Novartis AG announced it will buy Avidity Biosciences for $12 billion, with both boards unanimously approving the deal to close in the first half of 2026.
  • Avidity Biosciences Inc., developer of Antibody Oligonucleotide Conjugates, offers a platform Novartis said will advance its neuroscience strategy and complement its pipeline with potential first-in-class candidates.
  • The deal's terms show Avidity Biosciences Inc. stock surged roughly 42% after the announcement, representing a 46% premium to the Friday closing share price of $49.15 and a 62% premium to the 30‑day VWAP of $44.42.
  • SpinCo will be spun out to list its cardio programs with $270 million in cash, led by Kathleen Gallagher, SpinCo CEO, while Sarah Boyce, Avidity president and CEO, becomes board chair; the transaction is conditional on regulatory approvals and customary closing conditions.
  • Long‑term, Novartis AG said buying Avidity will support its long‑term neuroscience strategy to launch several neuro treatments in coming years, unlocking multi‑billion‑dollar opportunities with planned product launches before 2030 and recouping billions from lost patent sales.
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Seeking Alpha broke the news in United States on Monday, October 27, 2025.
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