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New leukaemia treatment hailed as 'milestone' in cancer management

  • The Flair trial, led by Dr Talha Munir at Leeds, studied 786 untreated chronic lymphocytic leukaemia patients across 96 UK cancer centres.
  • Researchers sought to assess if two targeted drugs, ibrutinib and venetoclax, could outperform standard chemotherapy by personalizing treatment based on cancer response.
  • After two years, 66% of patients receiving the new treatment showed no trace of cancer in their bone marrow, compared to 48% of those treated with chemotherapy and none treated with ibrutinib alone.
  • Dr Munir called the trial a “milestone” and stated chemotherapy-free treatment can be both more effective and better tolerated for patients.
  • The results suggest a shift towards kinder, personalized therapies for CLL, potentially improving survival and quality of life for thousands diagnosed annually in the UK.
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New leukaemia treatment hailed as ‘milestone’ for patients

After five years, 94% of patients were alive, with no disease progression.

·London, United Kingdom
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The Independent broke the news in London, United Kingdom on Sunday, June 15, 2025.
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