US EditionLithium Deficiency Linked to Alzheimer's Onset, Orotate Restores Memory in Mice
Researchers found that lithium deficiency impairs brain cells' ability to clear amyloid plaques and tau tangles, reversing cognitive decline in mice with lithium orotate treatment.
- Lithium deficiency may be linked to Alzheimer’s disease, according to research from Harvard University.
- The team found that lithium orotate can prevent memory loss in mice and does not bind to amyloid plaques.
- Experts stress the importance of clinical trials to explore lithium orotate's effects on humans, recognizing the study's findings as significant and novel.
- The Harvard team successfully restored memory function in mice by reintroducing lithium orotate, a less toxic compound, into their diet.
98 Articles
98 Articles
Lithium deficiency may be the hidden spark behind Alzheimer’s
Harvard scientists have uncovered that lithium, a naturally occurring element in the brain, may be the missing piece in understanding Alzheimer’s. Their decade-long research shows that lithium depletion—caused by amyloid plaques binding to it—triggers early brain changes that lead to memory loss. By testing new lithium compounds that evade plaque capture, they reversed Alzheimer’s-like damage and restored memory in mice at doses far lower than t…
Dementia breakthrough as scientists discover key deficiency could play crucial role in disease onset
Researchers at Harvard Medical School have identified a potential breakthrough in understanding Alzheimer's disease after discovering that insufficient lithium levels in the brain may play a crucial role in the condition's onset.The comprehensive study, spanning 10 years and published in Nature, demonstrates that lithium naturally exists in brain tissue where it helps preserve normal cellular function across all major cell types.The research tea…
Lithium could reverse Alzheimer’s disease, Harvard researchers find
Researchers at Harvard Medical School have discovered a relatively simple yet profound potential treatment for dementia. They found that dissipating levels of lithium may cause cognitive decline — and that small doses of the metal could restore brain health. The study, reported Wednesday in the journal Nature, could foretell enormous impacts for the world’s aging population. An estimated 55 million people worldwide, including 6 million in the Un…
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