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Colorado prepares to follow Oregon into psychedelic mushroom movement

  • In 2022, Colorado voters approved Proposition 122, legalizing natural psychedelics, while Oregon voters had approved legalizing psilocybin for therapeutic use in 2020, making them the first states to try administering psychedelics outside of clinical, religious, and underground settings in the U.S.
  • This shift is occurring against a backdrop where psychedelic mushrooms have a long history in Indigenous cultures, with Colorado law recognizing the potential cultural harm from commercialization, and the FDA has designated psilocybin a breakthrough therapy, yet psilocybin remains a Schedule I drug illegal under federal law except for clinical research.
  • Colorado's program, modeled after Oregon's, is preparing to authorize the state's first healing centers in late spring or early summer, where psychedelic mushrooms can be ingested under supervision, with regulators already issuing licenses for these facilities.
  • Tasia Poinsatte of the Healing Advocacy Fund noted that healing centers plan to offer sliding-scale pay options and discounts for veterans, Medicaid enrollees, and those with low incomes, but psychedelic treatments in Oregon are typically expensive, ranging from $1,000 to $3,000 per session and not covered by insurance.
  • While psilocybin shows promise for treating mental health disorders like depression and anxiety, William R. Smith cautioned that it has not yet been shown to be better than other advanced treatments, and Michael Hasselmo cautioned about psilocybin's risks, including the potential to accelerate psychosis development in those with genetic loading.
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Marijuana Moment broke the news in on Wednesday, March 26, 2025.
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