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Chocolate Compound Drug Reportedly Beats Tamiflu
HEBREW UNIVERSITY OF JERUSALEM, ISRAEL, AUG 6 – The new Theobromine-Arainosine drug combo targets a viral ion channel and neutralizes drug-resistant flu strains, offering a potential alternative to Tamiflu, researchers said.
Researchers at Hebrew University of Jerusalem published on August 4, 2025, a drug combo including a chocolate compound that outperforms Tamiflu against flu strains.
The team developed this treatment due to the increasing ineffectiveness of Tamiflu as influenza viruses mutate and resist existing drugs.
Theobromine and Arainosine block the M2 ion channel, a viral feature vital for replication, and the combo reduced viral RNA in lungs by over 75% in tests.
The treatment reduced viral RNA levels by 15,717-fold, significantly outperforming Tamiflu’s 3,077-fold reduction, and Prof. Isaiah Arkin emphasized that this represents more than simply an improved flu medication.
ViroBlock, a Hebrew University startup, is advancing this therapy toward human trials, indicating potential for broader antiviral applications beyond influenza.