MLN4924 Halts Renal Cancer by Stabilizing FBP1
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MLN4924 Halts Renal Cancer by Stabilizing FBP1
In a groundbreaking study set to redefine the therapeutic landscape of clear cell renal cell carcinoma (ccRCC), researchers have illuminated how MLN4924—a potent small molecule inhibitor—exerts its tumor-suppressive effects by stabilizing nuclear FBP1, a critical metabolic regulator within cancer cells. This revelation uncovers a sophisticated regulatory axis that not only curbs tumor metabolism but also halts aggressive tumor growth, offering f…
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