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Massive diphenhydramine overdose resulting in death

Summary by National Institutes of Health (NIH)…
Overdosage of diphenhydramine may result in the development of anticholinergic symptoms, seizures, and coma. A fatal outcome following a diphenhydramine overdose does not commonly occur. This report describes the largest documented overdosage of diphenhydramine (7.5 g) which resulted in the death of …

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National Institutes of Health (NIH)… broke the news in Washington, United States on Monday, May 26, 2025.
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