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Major Pharmacy Chain Closes All Locations Across U.S.

Rite Aid, a major U.S. pharmacy chain founded in Pennsylvania in 1962, officially closed all its stores nationwide by September 29, 2025.
The closures followed two Chapter 11 bankruptcy filings in October 2023 and May 2025 caused by high debt, declining sales, and opioid litigation costs.
In early 2022, Rite Aid reached its highest number of stores at 2,451, but by September 2, 2025, the count had sharply dropped to 89 across 12 states before the final closures.
CEO Matt Schroeder pointed to monetary difficulties worsened by the fast-changing dynamics in both the retail and healthcare sectors, while analyst Neil Saunders indicated that the result was anticipated.
Rite Aid's shutdown ended a 62-year run, transferring prescriptions to CVS and marking a significant shift in the U.S. pharmacy industry landscape.

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