US EditionDietary Control of Peripheral Adipose Storage Capacity Through Membrane Lipid Remodelling
GREATER LONDON, ENGLAND, JUL 9 – Researchers analyzed over 170,000 fat cells from 70 people and found weight loss removes damaged cells and boosts lipid recycling linked to improved metabolism.
7 Articles
7 Articles
Dietary control of peripheral adipose storage capacity through membrane lipid remodelling
Genetic and dietary cues are known drivers of obesity, yet how they converge at the molecular level is incompletely understood. Here we show that PPARγ supports hypertrophic expansion of adipose tissue via transcriptional control of LPCAT3, an endoplasmic reticulum (ER)-resident O-acyltransferase that selectively enriches diet-derived omega-6 polyunsaturated fatty acids (n-6 PUFAs) in the membrane lipidome. In mice fed a high-fat diet, lowering …
The research shows that, after a weight loss, there are alterations that do not recover at all. “You have to take the blame from the people,” sums up one expert
Weight loss clears out aging cells and boosts lipid recycling, study finds
Scientists have produced the first detailed characterization of the changes that weight loss causes in human fat tissue by analyzing hundreds of thousands of cells. They found a range of positive effects, including clearing out of damaged, aging cells, and increased metabolism of harmful fats.
Study Reveals the Benefits of Weight Loss on Adipose Tissue
Weight loss does more than just lower the numbers on the scale. According to a study published in the journal Nature, shedding pounds triggers a profound reconfiguration of adipose tissue, directly contributing to improvements in metabolic, cardiovascular, and immune health. The research analyzed cells from 70 individuals—before and after bariatric surgery—to understand, in detail, what happens to fat tissue during weight loss. Using advanced ce…
Detailed Map of Weight Loss Induced Changes in Adipose Tissue
Scientists have produced the first detailed characterization of the changes that weight loss (WL) causes in human adipose tissue (AT) by analyzing hundreds of thousands of cells from morbidly obese individuals undergoing weight loss surgery. They found a range of positive effects, including clearing out damaged, aging cells and increased metabolism of harmful fats. The team, headed by William R Scott, PhD, at the MRC Laboratory of Medical Scienc…
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- 50% of the sources lean Left, 50% of the sources are Center
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