Gene Expression After Asbestos Exposure Explains Development of Malignant Mesothelioma

Interview: Yaara Bou Melhem

Having been born in the 1980s and lived my entire life in Western Australia, the devastating legacy of the Wittenoom asbestos mines has always loomed large. This environmental and human tragedy, where more than three million tonnes of deadly mineral waste were dumped over 60 years ago, remains the largest contaminated site in the Southern…

The removal of multiplicative, systematic bias allows integration of breast cancer gene expression datasets – improving meta-analysis and prediction of prognosis - BMC Medical Genomics

The number of gene expression studies in the public domain is rapidly increasing, representing a highly valuable resource. However, dataset-specific bias precludes meta-analysis at the raw transcript level, even when the RNA is from comparable sources and has been processed on the same microarray platform using similar protocols. Here, we demonstrate, using Affymetrix data, that much of this bias can be removed, allowing multiple datasets to be …

Gene Expression After Asbestos Exposure Explains Development of Malignant Mesothelioma

Gene expression leading to alterations in the DNA caused by asbestos exposure may explain the development of Malignant Pleural Mesothelioma (MPM), a rare and aggressive cancer.

Legal Options Available to Asbestos Exposure Victims MyrtleBeachSC News

Asbestos exposure can create serious health complications, including mesothelioma, asbestosis, and lung cancer: conditions that often appear years after initial contact. The physical and emotional toll on asbestos exposure victims and their families can be significant. However, there are several ways to get justice and financial compensation from the liable parties. Whether the exposure occurred at a job or from contaminated products, victims ca…