Basal Stem-Like Cells Identified as Origin of Small Cell Lung Cancer in Lab Models

Basal stem-like cells identified as origin of small cell lung cancer in lab models

A new study reveals that small cell lung cancer (SCLC) likely begins in basal stem-like cells rather than in neuroendocrine cells, marking a major shift in the understanding of this aggressive disease that is often associated with smoking.

Lab Models Reveal Basal Stem-Like Cells as the Origin of Small Cell Lung

A groundbreaking study from Duke University has upended long-held assumptions about the origins of small cell lung cancer (SCLC), one of the deadliest forms of lung cancer predominantly linked to smoking. For decades, the prevailing consensus was that SCLC originates in neuroendocrine cells, highly specialized lung cells once thought to be the disease’s primary source. However, this new research reveals that SCLC more likely begins in basal stem…

Discovery overturns ideas about small cell lung cancer's start

New research marks a major shift in the understanding of small cell lung cancer, which is often associated with smoking.