New approach to tau protein clearance offers hope for Alzheimer's treatment

New approach to tau protein clearance offers hope for Alzheimer's treatment

USC Stem Cell scientists discover a new way to rid cells of toxic tau protein in a study involving mice and lab-grown human “mini-brains,” known as organoids.

"It can be measured and, unlike genetics, it can be changed," said Amy Kind, an international specialist in the study of exposoma and the social determinants of health and dementia, as she passed through Buenos Aires.

How to clear the toxic tau protein that can lead to Alzheimer’s and related diseases - USC Stem Cell

The neurotransmitter glutamate is essential for regulating everything from mood to memory, but it can also encourage a toxic buildup of the notorious tau protein, which can contribute to Alzheimer’s and related diseases. In a USC Stem Cell-led study published in Neuron, scientists describe a new approach for counteracting these devastating and often fatal neurodegenerative effects.

Brain Autopsies Reveal a Potential Culprit Behind Alzheimer's

Analysis of human brain tissue revealed differences in how immune cells behave in brains with Alzheimer's disease compared to healthy brains, indicating a potential new treatment target.

Alzheimer's breakthrough: Scientists discover why women more at risk of developing dementia than men

Scientists have discovered why women are more at risk of developing dementia than men in a new breakthrough for Alzheimer’s research.Research has shown that women are at greater risk because they are prone to higher levels of a toxic protein in the brain. It was previously thought that women were more likely to develop the disease because they live longer, however this now may not be the case.American scientists have said that women, who already…

Key protein identified for understanding and treating Alzheimer's disease

Researchers have identified a specific form of the tau protein that is responsible for mediating the toxicity of harmful protein clumps in human neurons and thus represents a target for future treatments / publication in 'Alzheimer's & Dementia'