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JCI Vascular smooth muscle cell–derived KIF13B inhibits proinflammatory responses to protect against atherosclerosis
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JCI Vascular smooth muscle cell–derived KIF13B inhibits proinflammatory responses to protect against atherosclerosis
Atherosclerotic cardiovascular disease (ASCVD) remains a leading cause of death worldwide, with plaque instability being a major culprit. Phenotypic switching of vascular smooth muscle cells (VSMCs) is a central event in atherosclerosis, driving both plaque progression and stability, yet the underlying mechanisms are incompletely understood, limiting drug development targeting this process. Kinesin family member 13B (KIF13B) has been implicated …
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