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Ivermectin-Loaded Oral Microemulsion for Oral Use
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Ivermectin-Loaded Oral Microemulsion for Oral Use
Abstract The oral bioavailability of marketed ivermectin (IVR) tablets is 50% compared to an oral hydroalcoholic solution. In this study, we developed an oral liquid microemulsion of IVR to improve compliance in pediatric patients. Oils, surfactants, and co-surfactants were screened and selected using solubility and emulsification tests. Using the selected oil, surfactant, and co-surfactant, a pseudo-ternary phase diagram was developed at surfac…
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