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Excess Weight Linked to Breast Cancer Risk in Postmenopausal Women with Cardiovascular Disease

EUROPE AND UNITED KINGDOM, JUL 7 – Each 5 kg/m2 BMI increase raises breast cancer risk by 31% in postmenopausal women with cardiovascular disease, compared to 13% in those without, study finds.

  • A recent study in CANCER found that each 5 kg/m2 BMI increase raises breast cancer risk by 31% in women with cardiovascular disease versus 13% without, highlighting differential impact.
  • Researchers analyzed data from over 168,000 postmenopausal women in EPIC and UK Biobank, with median follow-ups of about 11 years, to assess BMI's impact on breast cancer risk across cardiovascular health groups.
  • Analysis shows 6,793 breast cancer cases, with a 31% risk increase per BMI rise in women with cardiovascular disease versus 13% in those without.
  • Following these findings, risk-stratified breast cancer screening programs may target overweight women with cardiovascular disease, and future weight-loss trials should include this group for prevention.
  • Next, future weight-loss trials should include women with cardiovascular disease to inform breast cancer prevention strategies, encouraging broader risk-based screening research.
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Medical Xpress broke the news in on Monday, July 7, 2025.
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