US EditionExcess Weight Linked to Breast Cancer Risk in Postmenopausal Women with Cardiovascular Disease
EUROPE AND UNITED KINGDOM, JUL 7 – A 5 kg/m2 BMI increase raises breast cancer risk by 31% in postmenopausal women with cardiovascular disease, compared to 13% in those without, study shows.
- Recently, findings were published in the CANCER journal showing Heinz Freisling's team analyzed data from EPIC and UK Biobank on 168,547 postmenopausal women without disease at baseline.
- Higher BMI is a known risk factor for breast cancer in postmenopausal women, and excess weight raises risk for 12 cancers, including uterine and kidney, prompting shared risk factor research.
- A pooled analysis showed each 5 kg/m2 increase in BMI was linked to a 31% higher breast cancer risk in women with cardiovascular disease and 13% in others, adding 153 cases per 100,000 annually.
- Women with cardiovascular disease should discuss their cancer risk and healthy BMI targets with their healthcare provider, as weight control and lifestyle counseling may reduce breast cancer risk.
- To refine risk prediction, new BMI-specific waist circumference thresholds from the IAS and ICCR improved c-statistics by 0.7% in Validation Cohort 1 and 0.3% in Cohort 2, Aragaki et al. wrote.
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How body mass index affects breast cancer risk in postmenopausal women with and without cardiovascular disease
New research reveals that excess weight is linked to an especially high risk of developing breast cancer in postmenopausal women with cardiovascular disease. The findings are published in Cancer.
The relationship between weight and health is well established, and a new medical alert highlights the impact of overweight on the risk of breast cancer in women after menopause. In-depth research highlights a significant correlation between excess body fat and an increased incidence of this devastating disease. It is crucial to understand this weight limit for effective prevention and appropriate screening programs.
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