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Women's Health Expert Dr. Larkin Addresses Hormone Therapy ...

SPOKANE COUNTY, WASHINGTON, JUL 17 – The FDA will review hormone therapy risks after a study linked estrogen-progestin and estrogen-only therapies to specific breast cancer subtypes in over 42,000 women.

  • Researchers in JAMA Network Open found clear differences in associations between current estrogen-progestin therapy and luminal-like breast cancer subtypes, underscoring evidence of etiologic heterogeneity in carcinogenesis.
  • After widespread use, hormone replacement therapy has helped alleviate menopause symptoms like hot flashes and poor sleep quality, but use has plummeted amid concerns over rare side effects.
  • The study found OR, 2.51 for luminal A-like and 1.95 for luminal B/ERBB2-like subtypes in healthy-weight women using EPT, suggesting subtype-specific associations.
  • At the FDA meeting, Marty Makary signaled that prescriptions for hormone replacement therapy had plummeted in the United States, and he mentioned the halted Women’s Health Initiative trial as a factor involved.
  • The authors wrote that future studies on contemporary formulations, patterns of use, and routes of administration are warranted.
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56 Articles

ABC FOX MontanaABC FOX Montana
+24 Reposted by 24 other sources
Center

US may revise hormone replacement therapy warnings

US Food and Drug Administration Commissioner Marty Makary signaled Thursday that he is open to revising strict warning labels on Hormone Replacement Therapy, following testimony from experts who said the treatment's risks have long been exaggerated.

·Missoula, United States
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InsideNoVA.comInsideNoVA.com
+13 Reposted by 13 other sources
Center

US health experts reassess hormone replacement therapy risks

US health authorities on Thursday began a reassessment of the risks surrounding Hormone Replacement Therapy (HRT), a treatment used by menopausal women around the world but long clouded by fear over its side effects.

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Medical XpressMedical Xpress
+10 Reposted by 10 other sources
Center

US health experts to reassess hormone replacement therapy risks

US health authorities are set Thursday to reassess hormone replacement therapy (HRT), a treatment used by menopausal women around the world but long clouded by debate over its risks.

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ajmc.com broke the news in on Wednesday, July 16, 2025.
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