US EditionHealthy babies born in Britain after scientists used DNA from three people to avoid genetic disease
UNITED KINGDOM, JUL 25 – Eight babies born via three-person IVF in the UK show no signs of mitochondrial disease, a condition affecting 1 in 5,000 births, researchers report promising early health outcomes.
- On July 16, 2025, researchers from Newcastle announced the successful birth of eight healthy infants in the UK through pronuclear transfer, an innovative IVF method designed to lower the risk of mitochondrial diseases.
- The UK legalized pronuclear transfer in 2015 to help women with high-risk mitochondrial DNA mutations prevent passing on incurable diseases to their children.
- The babies were closely monitored from birth, showed normal development, and had undetectable or very low harmful mitochondrial DNA mutation levels well below disease thresholds.
- Professor Mary Herbert said the findings offer grounds for optimism but noted that follow-up studies are essential to assess long-term effects and address carryover of maternal mitochondria.
- This technique provides an important reproductive option for affected families and offers hope to many women facing mitochondrial disease risks, though prevention is not guaranteed.
324 Articles
324 Articles
Healthy Babies Born After Scientists Use DNA of 3 People to Prevent Inherited Diseases
Scientists at Newcastle University used a new IVF technique that combines a mother’s egg and father’s sperm with a second egg from a donor woman in order to prevent a child from inheriting mitochondrial DNA disease from their mother.
Revolutionary Science and Ancient Discoveries Unveiled | Science-Environment
Revolutionary Science and Ancient Discoveries Unveiled In a groundbreaking development, scientists from Newcastle University have announced the successful use of a three-person IVF technique. This innovative method has spared eight UK children from hereditary diseases. The procedure involves transferring the mother's fertilized egg nucleus and the father's sperm nucleus into a healthy donor's egg. However, the technique remains banned in the Uni…
In order to avoid a hereditary disease, an in vitro fertilization technique used the genetic material of a donor, in addition to those of mother and dad. The procedure, however, involved the formation and then the rejection of a healthy embryo.In Britain there are eight children born without a disease.
Babies Born With DNA From Three People Hailed As Breakthrough – But Questions Remain
The technique, called mitochondrial donation, was used to help 22 women who carry faulty genes that would otherwise pass serious genetic disorders – such as Leigh syndrome – to their children. The post Babies Born With DNA From Three People Hailed As Breakthrough – But Questions Remain appeared first on Study Finds.
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