Universal antivenom within reach thanks to man bitten by snakes over 200 times – on purpose
- Tim Friede, a US man, deliberately exposed himself to over 200 snakebites and hundreds of venom injections from 16 species over 18 years to develop immunity.
- His self-immunization aimed to produce broadly neutralising antibodies, addressing the challenge that current antivenoms only target individual snake species.
- Researchers, including Jacob Glanville and Peter Kwong, studied Friede's blood, identifying two broadly neutralising human antibodies combined with a molecule, varespladib, tested successfully in mice.
- This combination showed protection against venom from 13 genetically diverse venomous snakes, which experts described as an "unparalleled" breadth of protection with potential for broad antivenom use.
- Although human trials are years away, this research could lead to safer, near-universal antivenoms, improving treatment access in remote areas where snakebite deaths and injuries remain high.
68 Articles
68 Articles
The man who got bitten more than 200 times by poisonous snakes (and whose blood surprises scientists by its power as antidote)
The blood of an American man who deliberately injected snake poison for nearly two decades has “unprecedented” power as an antidote, according to scientists.In animal testing, antibodies in Tim Friede's blood proved to protect against deadly doses of poison from a wide range of species.Current therapies require the antidote to correspond to the specific snake species that bit the affected person.The feat Friede performed for 18 years could be an…
Man bitten 200 times by deadly snakes helps create life-saving antidote
A man from Wisconsin who endured more than 200 lethal snake bites and injected himself with over 700 small venom doses of some of the world’s deadliest serpents has been instrumental in the creation of an antidote that could save thousands of lives. Tom Friede, of Wisconsin, exposed himself to deadly venom for 18 years. He began with small doses and gradually increased the amounts he took to… Source
Man bitten by snakes 200 times could provide life-saving anti-venom breakthrough
Man bitten by snakes 200 times could provide life-saving anti-venom breakthrough - A man who has been bitten by snakes over 200 times could provide an “unparalleled” antivenom that could save countless lives
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