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From No Hope to a Potential Cure for a Deadly Blood Cancer
Ninety-Seven individuals suffering from advanced multiple myeloma participated in a final-attempt immunotherapy study conducted in recent years.
Doctors considered multiple myeloma incurable and fatal within about a year, with painful bone damage and no effective treatments remaining.
The immunotherapy, a CAR-T treatment developed by Legend Biotech, used engineered white blood cells to attack the cancer and revolutionized outcomes in blood cancers like leukemia.
Approximately one-third of patients experienced complete remission of their cancer that lasted for at least five years, leading experts like Dr. Norman Sharpless to acknowledge that this marks a significant shift toward considering multiple myeloma potentially curable.
This result raises hope for multiple myeloma patients despite the treatment's high cost exceeding US$555,000, and experts see potential cure if used earlier in therapy.