49ers All-Pro Linebacker Fred Warner Carted Off Following Gruesome Ankle Injury
Fred Warner suffered a severe right ankle injury early in the game and was ruled out, further depleting the 49ers' defense already missing Nick Bosa, officials said.
- On Sunday, Oct. 12, 2025, San Francisco 49ers middle linebacker Fred Warner was carted off during the first half in Tampa, leaving with a leg cast and ruled out in the locker room.
- On a 10-yard run with 7:48 left in the first quarter, Fred Warner's right ankle twisted after players fell into him and Ji'Ayir Brown rolled into the back of his ankle.
- The CBS broadcast briefly showed the replay once due to its gruesome nature, while almost the entire San Francisco 49ers bench cleared and multiple players knelt as medical staff tended to Warner.
- The 49ers, already shorthanded, lost another defensive leader as second-year linebacker Tatum Bethune entered to replace Warner during Week 6 at 4-1, deepening injury challenges.
- Warner's absence removes an elite, durable leader from the defense; he was five tackles shy of Patrick Willis' franchise record before the injury.
46 Articles
46 Articles
49ers WR Jauan Jennings Reveals All the Injuries He's Playing Through
There is no NFL team that is as injured as the San Francisco 49ers after week six of the 2025 season. Even their “healthy” players are battling through some sort of ailment. Wide receiver Jauan Jennings revealed after Sunday’s 30-19 loss to the Tampa Bay Buccaneers that he is playing through five broken ribs and both a high and low ankle sprain. Jennings revealed that he broke his ribs during the 49ers week four game against the Jacksonville J…

What the 49ers are saying after losing to the Buccaneers
The 49ers couldn’t overcome their season-long injury issues Sunday as they fell in Tampa to the Buccaneers 30-19. Fred Warner went down with a gruesome ankle injury in the first quarter, leaving the defense without its vocal leader in the middle. The offense settled for a quartet of field goals from Eddy Piñeiro alongside Christian McCaffrey’s first rushing touchdown of the season. The Bucs had two rushing scores and Baker Mayfield passed for tw…
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