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49ers Star Defensive End Nick Bosa Is Out for the Season with a Torn ACL, AP Source Says

Nick Bosa suffered his third ACL tear, ending his 2025 season after recording two sacks and 17 tackles in three games, marking his second season-ending ACL injury in the NFL.

  • Sunday, Nick Bosa will miss the remainder of the 2025 season after tearing the ACL in his right knee during the 49ers' win over the Arizona Cardinals, ESPN's Adam Schefter reported.
  • After a third-down pass rush, Nick Bosa walked off before halftime giving a thumbs-down, and an MRI later confirmed a clean tear of the ACL.
  • A reminder of Bosa's track record: Nick Bosa's achievements include five Pro Bowls, NFL Defensive Rookie of the Year 2019, Defensive Player of the Year 2022, and a league-leading 18.5 sacks in 2022.
  • With Bosa out, the San Francisco 49ers, already missing Brock Purdy, George Kittle, Brandon Aiyuk and Jauan Jennings, will lean on Bryce Huff, Sam Okuayinonu and Yetur Gross-Matos and host the Jaguars next Sunday.
  • Bosa's history shows this is his third torn ACL, after injuries at St. Thomas Aquinas High and a 2020 left-knee ACL tear during his NFL career.
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Unbeaten San Francisco 49ers face new challenge after Nick Bosa's season-ending injury

The San Francisco 49ers have started the season with three straight wins, overcoming injuries to key players.

·United States
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Newsweek broke the news in United States on Sunday, September 21, 2025.
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