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Brain Circuits Split Food Choices Between Sugar and Fat Cravings
Summary by Neuroscience News
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2 Articles
Brain Circuits Split Food Choices Between Sugar and Fat Cravings
A new study reveals that the brain uses two distinct neural pathways to regulate sugar and fat intake. In mice, glucoprivation—a drop in blood sugar levels—activates separate circuits in the hypothalamus: AMPK-regulated CRH neurons drive high-carbohydrate consumption, while MC4R-expressing neurons promote high-fat food intake.
Food intake in mammals is controlled by a complex neural system. Although several important neural pathways related to total calorie intake have been extensively studied, it remains unclear how food selection is regulated and how it affects overall calorie intake.
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