ESOC 2025: Combined Oral Contraceptives Triple Risk of Cryptogenic Stroke in Young Women, New Study Shows
- Researchers presented new findings on May 20, 2025, in Helsinki showing combined oral contraceptives triple cryptogenic stroke risk in young women.
- The SECRETO study, involving 268 women aged 18-49 with cryptogenic stroke and matched controls across 14 European centers, provided the data for this association.
- The study controlled for factors including age and common health conditions such as high blood pressure, tobacco use, migraine accompanied by auras, and excess abdominal fat, all recognized as stroke risk contributors.
- Use of oral contraceptives was linked to a threefold increase in stroke risk . Lead author Dr. Mine Sezgin noted that these results support previous research showing a connection between hormonal birth control and stroke in young women.
- The findings suggest clinicians should carefully assess stroke risk before prescribing combined OCs, especially in women with other vascular risk factors or stroke history.
43 Articles
43 Articles

ESOC 2025: Combined oral contraceptives triple risk of cryptogenic stroke in young women, new study shows
HELSINKI, May 20, 2025 /PRNewswire/ -- New research presented today at the European Stroke Organisation Conference (ESOC) 2025 revealed that the use of combined oral contraceptives (OCs) is associated with a threefold increase in the risk of cryptogenic ischaemic stroke…
Oral Contraceptives May Triple Stroke Risk in Young Women, New ESOC 2025 Study Finds
HELSINKI, May 21, 2025 /PRNewswire/ -- New research presented today at the European Stroke Organisation Conference (ESOC) 2025 revealed that the use of combined oral contraceptives (OCs) is associated with a threefold increase in the risk of cryptogenic ischaemic stroke (CIS) in young women.(1) The findings add to a growing body of evidence linking hormonal contraception to vascular risk in women of reproductive age. Cryptogenic ischaemic stroke…
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