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Enhancing Anti-CD3 mAb-Mediated Diabetes Remission in Autoimmune Diabetes through Regulation of Dynamin-Related Protein 1(Drp1)-mediated Mitochondrial Dynamics in Exhausted CD8+T-Cell Subpopulations

Summary by Stemwell Science News
The phenotypic and metabolic properties of two subsets of exhausted CD8+ T cells were analyzed in both humans and NOD mice. T-cell receptor (TCR) diversity and Bulk RNA sequencing provided insights into the transcriptomic profiles and TCR reactivity of these cells. [BMC Medicine] Full Article
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Enhancing Anti-CD3 mAb-Mediated Diabetes Remission in Autoimmune Diabetes through Regulation of Dynamin-Related Protein 1(Drp1)-mediated Mitochondrial Dynamics in Exhausted CD8+T-Cell Subpopulations

The phenotypic and metabolic properties of two subsets of exhausted CD8+ T cells were analyzed in both humans and NOD mice. T-cell receptor (TCR) diversity and Bulk RNA sequencing provided insights into the transcriptomic profiles and TCR reactivity of these cells. [BMC Medicine] Full Article

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Stemwell Science News broke the news in on Tuesday, April 1, 2025.
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