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EMG1 methyltransferase activity affects ribosome occupancy at KSHV uORFs
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EMG1 methyltransferase activity affects ribosome occupancy at KSHV uORFs
EMG1 methyltransferase activity affects ribosome occupancy at KSHV uORFs Viruses lack their own translational machinery and rely exclusively on the host cell for synthesis of viral proteins. Viruses have evolved diverse mechanisms to redirect the host cell translation apparatus to favor viral transcripts. A unique mechanism employed by Kaposi's sarcoma-associated herpesvirus (KSHV) involves manipulation of cellular ribosome composition, producin…
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