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Eli Lilly to Acquire Ajax Therapeutics for up to $2.3 Billion

Ajax’s lead drug is a Phase 1 Type II JAK2 inhibitor that Lilly says could offer deeper, more durable control for myelofibrosis and other MPNs.

  • On Monday, Eli Lilly and Company announced a definitive agreement to acquire cancer drug developer Ajax Therapeutics for up to $2.3 billion in cash.
  • Ajax's lead program, AJ1-11095, is a first-in-class Type II JAK2 inhibitor designed to provide deeper and more durable disease control than existing Type I therapies for myelofibrosis patients.
  • Lilly is continuing an active dealmaking spree to expand its oncology pipeline, having acquired Kelonia Therapeutics for $7 billion last week.
  • Jacob Van Naarden, president of Lilly Oncology, stated the firm intends to use its expertise to "hopefully deliver another important new medicine to patients and hematologists."
  • Analyst Trung Huynh wrote the deal aligns with Lilly's "land grab M&A playbook" of acquiring "differentiated, mechanistically compelling" assets early, despite the company's previous internal JAK2 inhibitor failure.
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Eli Lilly to acquire Ajax Therapeutics for up to $2.3 billion

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biopharmadive.com broke the news on Monday, April 27, 2026.
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