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Merck, Wellcome Partner with Global Health Group to Make Ebola Vaccine for Clinical Trials
The collaboration is backed by up to $8.5 million from CEPI and aims to produce doses for early-stage testing.
On Thursday, the Coalition for Epidemic Preparedness Innovations announced an $8.5 million commitment to Singapore-based Hilleman Laboratories to manufacture doses of an experimental Bundibugyo Ebola vaccine for clinical trials.
The Bundibugyo strain currently lacks any licensed vaccine, fueling a fast-spreading outbreak in the Democratic Republic of the Congo that officials describe as a humanitarian crisis.
Hilleman Laboratories will use material developed by the International AIDS Vaccine Initiative to produce doses, building on the manufacturing process for Merck's Zaire Ebola vaccine.
CEPI Chief Executive Richard Hatchett said "with Bundibugyo virus cases rising at worrying speed, the epidemic is fast becoming a humanitarian crisis." Full production takes roughly 6 months, though trial doses should arrive sooner.
Beyond this effort, CEPI is investing up to $8.6 million in an Oxford University vaccine candidate now in human trials and has committed up to $50 million for a Moderna collaboration.
A vaccine against Ebola, presented by WHO as "the most promising" against the epidemic still raging in the Democratic Republic of the Congo, will be developed by Hilleman Laboratories, based in Singapore, announced this group on Thursday. ...