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Digital PCR can reliably quantify stable deep molecular remission of chronic myeloid leukemia

Summary by News Medical
Researchers have found that the clinical application of BCR::ABL1 digital PCR can reliably quantify stable deep molecular remission of chronic myeloid leukemia (CML), which will help to determine for which patients chronic drug treatment could potentially be discontinued.

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Digital PCR can reliably quantify stable deep molecular remission of chronic myeloid leukemia

Researchers have found that the clinical application of BCR::ABL1 digital PCR can reliably quantify stable deep molecular remission of chronic myeloid leukemia (CML), which will help to determine for which patients chronic drug treatment could potentially be discontinued.

·United States
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Scienmag: Latest Science and Health NewsScienmag: Latest Science and Health News
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Digital PCR Accurately Assesses Drug Discontinuation in Remission for

Philadelphia, March 27, 2025 – In a groundbreaking study published in The Journal of Molecular Diagnostics, researchers have successfully demonstrated that digital PCR technology can reliably quantify the stable deep molecular remission in patients suffering from chronic myeloid leukemia (CML). This advancement is crucial as it opens up the possibility for some long-term CML patients to safely discontinue their chronic drug treatments. The uniqu…

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Medical XpressMedical Xpress

Digital PCR identifies leukemia patients who can stop drug treatment

Researchers have found that the clinical application of BCR::ABL1 digital PCR can reliably quantify stable deep molecular remission of chronic myeloid leukemia (CML), which will help to determine for which patients chronic drug treatment could potentially be discontinued. This transcript that is unique for CML is more sensitive and accurate than the current standard, real-time quantitative PCR (RT-qPCR), for detecting ultralow levels of residual…

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Medical Xpress broke the news in on Thursday, March 27, 2025.
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