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Development of vacuum compression molded tablets with rapid drug release and a comparison of dissolution profiles between molded and FDM 3D-printed tablets - Pharma Excipients

Summary by Pharma Excipients
Abstract In recent years, there has been much interest in the development of personalized and on-demand tablets by FDM 3D-printing of melt-extruded filaments. Alternatively, the filaments can also be converted into molded tablets. However, drug release rates from tablets produced by both methods are very slow and not amenable to immediate-release drug products. We previously reported a novel approach called acid-base supersolubilization (ABS), …
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Development of vacuum compression molded tablets with rapid drug release and a comparison of dissolution profiles between molded and FDM 3D-printed tablets - Pharma Excipients

Abstract In recent years, there has been much interest in the development of personalized and on-demand tablets by FDM 3D-printing of melt-extruded filaments. Alternatively, the filaments can also be converted into molded tablets. However, drug release rates from tablets produced by both methods are very slow and not amenable to immediate-release drug products. We previously reported a novel approach called acid-base supersolubilization (ABS), …

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Pharma Excipients broke the news in on Thursday, April 3, 2025.
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