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Covid in pregnancy tied to autism, developmental issues, study says

Researchers found maternal COVID-19 during pregnancy raises autism and neurodevelopmental disorder risk by 29%, especially when infection occurs in the third trimester.

  • A study in Obstetrics & Gynecology by Mass General Brigham found children born to mothers with Covid-19 during pregnancy may be more likely to receive neurodevelopmental diagnoses, including autism.
  • Using an early-pandemic, largely unvaccinated cohort, the team analyzed births from March 2020–May 2021 with about 93% of mothers unvaccinated, building on prior literature on maternal infections and immune activation.
  • Looking at exposed versus unexposed subgroups, the team found that about 16.3% of 861 children born to SARS‑CoV‑2–positive mothers received neurodevelopmental diagnoses by age three, compared with about 9.7% of 17,263 unexposed children.
  • Dr. Lydia Shook urged parental awareness for proper evaluation, while researchers stressed preventing Covid-19 in pregnancy and Roy Perlis noted the overall risk likely remains low.
  • Risk was highest for boys and after third‑trimester infection, with authors citing biological evidence and urging more study amid vaccine guidance debate and public health messaging.
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Children exposed to Covid in the womb face higher risk of autism, study finds

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The risk is higher for those who contracted the infection during the third trimester of pregnancy

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The Washington Post broke the news in on Thursday, October 30, 2025.
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