US EditionModerna study shows immune response in older adults for a combo flu and COVID-19 shot
- Moderna researchers reported on May 7, 2025, that their mRNA-based combo flu and COVID-19 shot generated antibodies in people aged 50 and older in a company-sponsored trial of 8,000 participants.
- The study measured antibodies after 29 days, but the FDA requested additional data showing how much the shot lowers the risk of disease to better assess protection.
- The combo shot induced a stronger immune response than existing standalone vaccines against COVID-19 and most flu strains, with side effects limited to injection site pain, fatigue, and headaches.
- Dr. Greg Poland, who was not part of the study, emphasized the need for data demonstrating how effective the new vaccine is, aligning with the FDA’s position, while also expressing skepticism about whether a combined flu and COVID-19 shot would become widely accepted.
- Moderna postponed vaccine approval to 2026 as the FDA's data request introduces uncertainty, but the company believes mRNA technology could speed up flu shot production compared to traditional methods.
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Moderna's Combo Flu and COVID Shot Shows Promise
Key Takeaways
Moderna Study Shows Immune Response in Older Adults for a Combo Flu and COVID-19 Shot
A combination shot for flu and COVID-19 using messenger RNA generated antibodies in a study, but U.S. government regulators want to see data on whether the new vaccine protects people from getting sick.
·Japan
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The hunt for a universal flu vaccine that can also protect against future pandemics has gained new fuel. But why use an old vaccine technology? The science room also deals with snakebites, a test for post-covid and unequal health.
·Stockholm, Sweden
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