US EditionControlled release of amitriptyline via the transdermal route using SmartReservoirs and hydrogel-forming microneedles - Pharma Excipients
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Controlled release of amitriptyline via the transdermal route using SmartReservoirs and hydrogel-forming microneedles - Pharma Excipients
Abstract SmartReservoirs (SRs) are novel drug reservoirs made from a cellulose-based matrix for hydrogel-forming microneedles (HF-MNs). SRs can incorporate drug molecules within a cellulose-based matrix in amorphous form. This significantly improves the solubility of poorly soluble drugs, which enhances drug delivery by allowing for rapid dissolution and absorption once the dosage form is administered. In contrast to improving the solubility of …
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