US EditionCompound blocks replication of cutaneous HPVs without harming host cells
TARTU COUNTY, ESTONIA, JUL 8 – NSC51349 inhibits replication of cutaneous HPV types in lab tests without harming host cells, showing potential for treating infections unmet by current vaccines, researchers said.
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Compound blocks replication of cutaneous HPVs without harming host cells
Human papillomaviruses, or HPVs, can cause dangerous infections in the skin and mucous membranes and may lead to cancer. Vaccines that prevent mucosal HPV infections aren't effective against cutaneous infections, which can cause serious diseases, particularly in immunocompromised people.
Cutaneous HPV Blocked by Small Molecule, Opening Door to Antivirals
Cutaneous human papillomaviruses (HPVs)—skin-infecting relatives of the better-known mucosal HPVs—cause persistent infections that may contribute to skin cancers, especially in immunocompromised people. However, unlike mucosal HPVs, they remain beyond the reach of existing vaccines, and no antiviral treatments exist. Now, researchers at the University of Tartu in Estonia have uncovered a small molecule compound that could fill this therapeutic g…
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