US EditionConcurrent activation of striatal direct and indirect pathways during action initiation
- Researchers reported on April 17, 2025, that common medications may delay Parkinson's disease symptom onset.
- Researchers at Cedars-Sinai sought to determine if common drugs slowed Parkinson's progress between 2010 and 2021.
- The study evaluated data from over 1,200 Parkinson's patients taking drugs for pain, high blood pressure, and cholesterol.
- Dr. Michele Tagliati stated that the medications studied controlled inflammation, potentially delaying Parkinson's development.
- Patients taking NSAIDs, statins, and beta blockers experienced symptom delays of 8.2, 9.3, and 9.6 years, respectively.
38 Articles
38 Articles
Concurrent activation of striatal direct and indirect pathways during action initiation
In mice performing an operant task, increases in neural activity in direct- and indirect-pathway spiny projection neurons (SPNs) are associated with action initiation but not with inactivity, and concurrent activation of SPNs from both pathways in one hemisphere precedes the initiation of contraversive movements. The prevailing view of the functional organization of the basal ganglia, brain areas involved in movement control, is that there are t…
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Common Meds Appear To Delay Onset Of Parkinson's Disease
Key Takeaways
Common Meds Appear To Delay Onset Of Parkinson’s Disease
Key Takeaways Common drugs used to treat chronic ailments appear to delay the onset of Parkinson’s symptomsAspirin, ibuprofen, statins and beta blockers were all associated with a delay in Parkinson’s symptomsThis delay gave people nearly a decade’s relief from the onset of symptoms THURSDAY, April 17, 2025 (HealthDay News) -- Common medications like aspirin, ibuprofen,
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