US EditionClemastine Fumarate Accelerates Accumulation of Disability in Progressive Multiple Sclerosis by Enhancing Pyroptosis
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Antihistamine clemastine may worsen MS disease progression
Clemastine fumarate, an antihistamine, boosted disease progression by more than five times in adults with progressive multiple sclerosis (MS), according to data from a Phase 1/2 trial. “Likely nobody in […] The post Antihistamine clemastine may worsen MS disease progression appeared first on Multiple Sclerosis News Today.
Clemastine Fumarate Accelerates Accumulation of Disability in Progressive Multiple Sclerosis by Enhancing Pyroptosis
Investigators identified pyroptosis as a likely mechanism of central nervous system injury underlying progressing independently of relapse activity even outside of clemastine toxicity. [Journal of Clinical Investigation] Full Article
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