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Colts Find a Way Against Arizona, Push Record to AFC-Best 5-1

The Colts scored 31 points with Jonathan Taylor rushing for 123 yards and a fourth-quarter touchdown to secure the AFC South lead, overcoming Cardinals’ quarterback injury challenges.

  • On Sunday, Oct. 12, 2025, the Indianapolis Colts rallied at Lucas Oil Stadium to beat the Arizona Cardinals 31-27, overturning a late Arizona lead.
  • With Kyler Murray inactive, Jacoby Brissett started as injuries mounted, including Marvin Harrison Jr.'s concussion and Travis Vokolek's neck injury, while Jonathan Gannon was fined $100,000.
  • Jacoby Brissett completed 27 of 44 passes for 320 yards with two touchdowns and an interception, Daniel Jones finished 22 of 30 for 212 yards with two touchdowns, and Jonathan Taylor rushed 21 times for 123 yards and scored the decisive fourth-quarter touchdown.
  • Indy is 5-1 and remained perfect at Lucas Oil Stadium, extending a six-game home streak while the Colts will head to Los Angeles to play the Chargers and Arizona returns home to face the Green Bay Packers.
  • BetMGM lines show the Indianapolis Colts have scored at least 20 points each game, and ESPN's matchup predictor gives them a 65.3% chance to win.
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The Indianapolis Colts celebrated their fifth win in the National Football League (NFL) against the Arizona Cardinals in the sixth season game.The home team with Left Tackle Bernhard Raimann won on Sunday 31:27. The decision in a multi-leadership game brought a touchdown from runningback Jonathan Taylor in the middle of the final quarter.Next Sunday, the Colts, who have scored their best season start since 2009, will compete with the Los Angeles…

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Indy Star broke the news in Indianapolis, United States on Sunday, October 12, 2025.
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