The U.S. Food and Drug Administration on Wednesday authorized booster doses of the COVID-19 vaccines from Moderna Inc (MRNA.O) and Johnson & Johnson (JNJ.N), and said Americans can choose a different shot than their original inoculation as a booster.

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U.S. FDA clears Moderna and J&J boosters, backs 'mix-and-match' strategy

INDIANAPOLIS – Quenton Nelson is on the clock, but might not be for long.The Indianapolis Colts’ All-Pro left guard was one of three players designated for a return to practice Wednesday – that opens a 21-day window for a player on the injured reserve list to practice – and there’s a chance the next step will be a major one.

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Colts’ notebook: Quenton Nelson returns to practice, has chance to return vs. Niners

ST. CHARLES, Mo.-- Nearly 30 years after the so-called "I-70 killer" terrorized the Midwest, St. Charles Police have released an updated aged-enhanced photo to try and generate new leads in the cold case. The law enforcement agencies involved with the case plan to have a meeting next month to discuss the investigation. There is a $25,000 reward that is still being offered for information involving the case.

Fox 2 Now St Louis

New sketch of ‘I-70 Killer’ hopes to generate leads in Missouri cold cases

PHILADELPHIA (AP) — Prosecutors pursuing the case against a man accused of raping a woman on a commuter train last week don’t anticipate charging fellow passengers for not intervening, a spokesperson for the suburban Philadelphia district attorney said.

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Charges unlikely for riders who saw Philadelphia train rape

Arizona on Wednesday reported 1,991 additional confirmed COVID-19 cases and 47 more deaths as virus-related hospitalizations increased.

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Arizona reports 1,991 additional COVID cases, 47 more deaths

One in eight women in the U.S. will develop breast cancer over the course of her lifetime, a statistic that became all too real for Holly Daugherty when she was diagnosed last year.“This process has made me sift through the important things and the unimportant things in life,” Daugherty said.‘Breast Cancer’ were two words Daugherty knew well.

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Hoosier woman beats breast cancer thanks to early detection; here’s what to know

INDIANAPOLIS -- IMPD continues to investigate a homicide on the University of Indianapolis campus.The deadly shooting took place Tuesday night.The victim was found in this parking lot outside a freshman dorm on Campus Drive.Seeing flashing lights and a man shot in the abdomen outside their dorm windows Tuesday night was an alarming experience for UIndy students.

Students react to homicide at UIndy; call for greater communication about violence on campus

INDIANAPOLIS -- Indianapolis firefighters responded to a house fire on the near northeast side Wednesday morning.Crews were dispatched around 3:20 a.m. to a vacant house fire near E. 25th Street and Dr. Andrew J. Brown Avenue.Officials tell us the first and second floors of the house were engulfed when crews arrived. They say they experienced some difficulty in getting all the flames out.

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