What is glioblastoma, the aggressive brain cancer that killed former U.S. Rep. Mia Love?

What is glioblastoma, the aggressive brain cancer that killed former U.S. Rep. Mia Love?

Former U.S. Rep. Mia Love, the first Black Republican woman elected to Congress, passed away at 49 after a battle with glioblastoma, an aggressive brain cancer. Despite undergoing surgery and immunotherapy in a clinical trial, the cancer ultimately proved resistant to treatment, highlighting the challenges of this incurable disease. The post What is glioblastoma, the aggressive brain cancer that killed former U.S. Rep. Mia Love? appeared first o…

Study establishes cell death as a driving force in glioblastoma

Glioblastoma, one of the most aggressive and lethal brain cancers, has a five-year survival rate of only 6.9%, according to the National Brain Tumor Society. While the relationship between glioblastoma and cell death, also called necrosis, has been established, it had remained unclear whether it contributed to cancer growth or was merely a byproduct of the disease, said Daniel J Brat, MD, Ph.D., chair and the Magerstadt Professor of Pathology, w…

Breakthrough in Brain Cancer Treatment: New Therapy Offers Hope for Patients

Calidi Biotherapeutics and City of Hope are advancing CLD-101, a novel therapy for recurrent high-grade glioma, showing promise in Phase 1 clinical trials. The trial is the first to test a multi-dose regimen of neural stem cell-based oncolytic virotherapy, delivering up to four weekly intracerebral doses. Fourteen participants have tolerated the treatment well, signaling new hope in tackling aggressive brain cancer. A $12 million grant from the …