Evaluating the safety and efficacy of a smallpox vaccine for preventing mpox

Evaluating the safety and efficacy of a smallpox vaccine for preventing mpox

The recent global monkeypox (mpox) outbreak, with a new and aggressive variant, has underscored the dire need for safe, broadly effective, and accessible vaccines. The LC16m8 vaccine, an attenuated vaccinia virus strain originally developed for smallpox, is a promising option for countering the mpox virus. Exploring this potential further, researchers employed a cross-species immunological analysis to provide new insights into LC16m8's immunogen…

Early trials of smallpox vaccine against mpox show positive safety and efficacy results

In recent years, the world has seen a surge in new and deadly infectious diseases, posing a major threat to global health. Outbreaks of COVID-19, H1N1 (swine flu), Ebola, Zika, and monkeypox are a stark reminder of our vulnerability.

Evaluating smallpox vaccine to prevent mpox.

In recent years, the world has seen a rise in new and deadly infectious diseases, posing a significant threat to global health. Outbreaks of COVID-19, H1N1 (swine flu), Ebola, Zika, and mpox highlight our vulnerability. While some of these viruses are recent and relatively unknown, others, like mpox (MPXV), have been around since the 1970s but have been confined to parts of Africa. However, the recent global outbreak of mpox—caused by a newly id…

Repositioning Smallpox Vaccines for a New Threat: Mpox

As the world continues to face the evolving threat of infectious diseases, including emerging zoonoses like mpox (formerly monkeypox), scientists are racing to develop vaccines that are not only safe [...] Read the rest of Repositioning Smallpox Vaccines for a New Threat: Mpox at Global Biodefense

Assessing the Safety and Effectiveness of a Smallpox Vaccine in Preventing

In recent years, the global health landscape has been dramatically reshaped by a series of unexpected and deadly infectious disease outbreaks. While much of the focus has been on novel pathogens like SARS-CoV-2, the monkeypox virus (commonly termed mpox) has quietly evolved from being a localized endemic pathogen in parts of Africa to a burgeoning international threat. The ongoing mpox outbreak is fueled by newly emergent viral variants exhibiti…